Diet Material

Product Description

Our Anti-Obesity Material is universal ingredient for health.

It contains an active ingredient called phytostenone (JP PATPEND,examination request).

We produce phytostenone by our original fermentation technique (JP PATPEND).

Characteristics

● Phytostenone significantly reduce visceral fat and relieve obesity.

● Phytostenone has two effects, beta-oxidation increase effect and fat transfer inhibition effect.

● Phytostenone has good lipid solubility, you can have better effect by taking it with fat.

Effect of Anti-Obesity Material in body weights gain.

  High fat diet with the addition of 0.5% Anti-Obesity Material fed group showed more     significant repression in body weights gain than the high fat control group. And body weights of them after 8 weeks weresimilar to those of the normal control group.

Effect of Anti-Obesity Material in body fat

  High fat diet with the addition of 0.5% Anti-Obesity Material fed group showed significant reduction in weightsof visceral fat and subcutaneous fat after 8 weeks.

SAFETY TEST

① It is heard that plants, especially Cattail※1, contain phytostenone, but all of plants contains a little bit. Therefore we carried outthe safety tests in accordance with the guideline of Ministry of Health, Labour and Welfare. ※1 Cattail grow gregariously around  swamps and ponds. It is cultivated in Chikugo-River basin of Saga Prefecture in Japan.

② Single dose oral toxicity test LD*0 : More than 2,**0mg/kg

③ 1 week continuous administration(rats : male/female) 1,**0mg/kg/day : Nothing abnormal detected on performance status, body weight, urinary test, blood biochemical examination, organ weight and necropsy

④ Genotoxicity testMutagenicity test(5 bacterial species) and Chromosomal aberration test : Negative

⑤ Multiple oral administration(mouse / male) 1,**0mg/kg/day : Nothing abnormal detected on performance status, body weight,blood biochemical examination, excretion test and organ weight.